Drugs used to treat high blood pressure and chest pain are often prescribed Merck’s simvastatin, but thousands of people are to have their dose reduced from 40 to 20mg because of serious side effects.
Despite advocates saying that everyone over 50 should take statins, the side effects are well-documented and include: muscle problems such as pain, tenderness, weakness and cramps and more rarely muscle breakdown leading to kidney damage.
R. Baselt published these findings four years ago, see: Disposition of Toxic Drugs and Chemicals in Man, 8th edition, Biomedical Publications, Foster City, CA, 2008, pp. 1431–3.
The Medicines and Healthcare products Regulatory Agency (MHRA) has produced a patient leaflet for the first time to inform people of the changes being made.